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Nanomedicine is a formidable technique that has the potential to reduce disease burdens by developing nanoparticle-based carriers and vaccinations. A team of interdisciplinary experts looked at its function in coronavirus disease diagnostics,
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Applied Technology Review | Sunday, March 13, 2022
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Diverse nanomaterials have been used to make exciting improvements in COVID-19 prevention, diagnosis, and therapy.
Fremont, CA: Nanomedicine is a formidable technique that has the potential to reduce disease burdens by developing nanoparticle-based carriers and vaccinations. A team of interdisciplinary experts looked at its function in coronavirus disease diagnostics, therapies, strategies, and future views in recent research. While vaccines are being produced at an unprecedented rate, with some now licensed and in use, therapeutic improvements that can help persons infected with the virus avoid severe sickness are still needed.
Nanomedicine is a formidable technique that has the potential to reduce disease burdens by developing nanoparticle-based carriers and vaccinations. A team of interdisciplinary experts looked at its function in coronavirus disease diagnostics, therapies, strategies, and future views in recent research. While vaccines are being produced at an unprecedented rate, with some now licensed and in use, therapeutic improvements that can help persons infected with the virus avoid severe sickness are still needed.
COVID-19 is a diverse disease with numerous clinical symptoms, posing a significant challenge to healthcare providers in determining the cause and treating patients. To understand the host-pathogen interaction and disease, develop optimum assays, and design successful medications and therapies, a variety of methodologies, strategies, and technologies are necessary. Nanotechnology-based tools have been shown to be effective against a range of pathogens in preclinical investigations, including respiratory viruses, herpes virus, human papillomavirus, and HIV. In this context, nanotechnology is a top priority for assisting with COVID-19.
Nanotechnology based Covid-19 treatment
The reviewers outlined the strategy for developing novel nanotherapeutic materials to improve COVID-19 therapy efficacy. These included the development of biodegradable, non-toxic, and stable nanoparticles that could be employed in the lung with little pulmonary toxicity during treatment, surface modification of nanoparticles by conjugation of PEG as a capping agent, and targeting moieties to reduce therapy side effects.
Role of nanotechnology in developing vaccines
Nanovaccines, a novel type of vaccine that uses nanoparticles to deliver antigens into the human body, have been developed. Nanoparticles have been shown to target both adaptive and innate immune systems at the cellular level. With configurable physical antigen loading, the nanoparticles can deliver or act as an intrinsic adjuvant. COVID-19 mRNA-based vaccines are encapsulated in positively charged lipid nanoparticles, resulting in RNase-resistant, stable self-assembling particles that may be injected in a variety of ways.
Future use of Nanotechnology for Covid-19
When considering the unanswered questions, the reviewers mentioned high-mutating RNA viruses, which require a quick and firm approach to combat. Overall, the importance of nanotechnology and nanoscience cannot be overstated, but researchers have cautioned that these promising materials could cause serious problems in the lungs and respiratory systems. Successful combination therapy involving nano-drug co-delivery devices, on the other hand, could be a viable solution to combating heterogeneous COVID-19.